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当前位置: 首页 > 产品中心 > Sandwich_method_ELISA > IBL/hCG ELISA/RE52191/
商品详细IBL/hCG ELISA/RE52191/
IBL/hCG ELISA/RE52191/
IBL/hCG ELISA/RE52191/
商品编号: RE52191
品牌: TECAN
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 夹心法ELISA
公司分类: Sandwich_method_ELISA
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Kitsize12x8
MethodELISA
Incubationtime1x30min,1x10min
Standardrange5-1000mIU/mL
Specimen/Volumes25µLSerum,plasma
Substrate/isotopeTMB,450nm
RegulatoryStatus:EU:CE
Detailsfor: hCGELISA
ThehCGELISAisanenzymeimmunoassayforthequantitativeinvitrodiagnosticmeasurementofintacthumanchorionicgonadotropin(hCG)inserumorplasma.

ChorionicGonadotropin(hCG)isaglycoproteinhormonewhichisnormallyproducedbytheplacentaduringpregnancy.Afterconception,thehCGconcentrationincreasesrapidlytoreachapeakneartheendofthefirsttrimester.Highconcentrationsareobservedthroughoutpregnancy.Afterdelivery,hCGlevelsfallrapidlyandbecomeundetectableafterafewdays.
StructurallyintacthCGmoleculesarecomposedofanalphaandabetasubunitwithamolucularweightof38.4kDa.Thealphasubunitisnearlyidenticaltothealphasubunitsofotherglycoproteinhormones,suchasThyroidStimulatingHormone(TSH),LuteinizingHormone(LH),andFollicleStimulatingHormone(FSH):ThedifferencesinthebetasubunitoftherespectivehormonesaccountfortheirBIOLOGicalspecificityandimmunochemicaldistinctiveness.MonoclonalantibodiesrecognizinguniquesitesonthebetachainofthehCGmoleculeareessentialfordifferentiationbetweenhCGandLH,FSHandTSH.

hCGAssaysareusedfortheearlydetectionofpregnancy.
1.InadditiontotheelevatedhCGlevelsduringpregnancy,highconcentrationsofhCGmaybeassociatedwithneoplasmsoftrophoblasticandnontrophoblasticoriginsuchashydatiformmole,chorionepithelioma,embryonalcellcarcinoma,andmanyothers.

2.HCGiscommonlyelevatedindifferenttesticulartumorsandisthususedasatumorMarkerfortesticulartumorsincombinationwithAFP.ThereisagoodcorrelationbetweenchangesinhCGlevelsandresponsetotherapy.

3.Extragonadalgerm-cellcancersintheabsenceofclinicallyorultrasonographicallydetectabletesticularabnormalitieshavebeeinobservedaswell.Over50%ofpatientswithmalignantinsulinomashaveelevatedhCGlevels:thehormoneisnotdetectedinassociationwithbenignadenomas.EctopicsecretionofhCGalsohavebeenfoundinasmallpercentageofpatientswithadenocarcinomaoftheovary,pancreasandstomach,hepatomas,andislet-cellcarcinomas.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.
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